Welcome to the Amira-Avizo Software Use Case Gallery

The elongate-necked aquatic plesiosaurs existed for 135 Myr during the Mesozoic. The function of this elongate neck is a point of debate. Using computed tomography and three-dimensional (3D) modelling, the range of motion (ROM) of the plesiosaur Nichollssaura borealis neck was assessed. To quantify the ROM, the intervertebral mobility was measured along the cervical vertebral column. This was done by manipulating the 3D models in the lateral and dorsoventral directions during two tri... Read more

Ptychographic X-ray computed tomography (PXCT) is a quantitative imaging modality that non-destructively maps the 3D electron density inside an object with tens of nanometers spatial resolution. This method provides unique access to the morphology and structure of the osteocyte lacuno-canalicular network (LCN) and nanoscale density of the tissue in the vicinity of an osteocyte lacuna.  Our findings indicate that PXCT can non-destructively provide detailed, nanoscale information on the 3D org... Read more

Combined expansion and lattice light sheet microscopy enables high
speed, nanoscale molecular imaging of neural circuits over large volumes.

Optical and electron microscopy have made tremendous inroads in understanding the complexity of the brain, but the former offers insufficient resolution to reveal subcellular details and the latter lacks the throughput and molecular contrast to visualize specific molecular constituents over mm-scale or larger dimensions. We combined expansio... Read more

Cyclostome bryozoans are an ancient group of marine colonial suspension-feeders comprising approximately 700 extant species. Previous morphological studies are mainly restricted to skeletal characters whereas data on soft tissues obtained by state-of-the-art methods are still lacking. In order to contribute to issues related to cyclostome ground pattern reconstruction, we analyzed the morphology of the neuromuscular system Cinctipora elegans by means of immunocytochemical staining,... Read more

Acetabular fracture surgery is directed toward anatomical reduction and stable fixation to allow for the early functional rehabilitation of an injured hip joint. Recent biomechanical investigations have shown the superiority of using an additional screw in the infraacetabular (IA) region, thereby transfixing the separated columns to strengthen the construct by closing the periacetabular fixation frame. However, the inter-individual existence and variance concerning secure IA screw corridors a... Read more

The tongue, with fleshy, muscular, and bony components, is an innovation of the earliest land-dwelling vertebrates with key functions in both feeding and respiration. Here, we bring together evidence from preserved hyoid elements from dinosaurs and outgroup archosaurs, including pterosaurs, with enhanced contrast x-ray computed tomography data from extant taxa. Midline ossification is a key component of the origin of an avian hyoid. The elaboration of the avian tongue includes the evolution o... Read more

Core@shell Fe@Fe₃O₄ nanoparticles (NPs) are synthesized via the thermal decomposition of iron pentacarbonyl (Fe(CO)₅) in the presence either of oleylamine (OAm) or a mixture of OAm and oleic acid (OA). The heterostructured nanocomposites formed do so by a postsynthetic modification of isolated Fe seeds. This proves the versatility of the coating procedure and represents a significant advantage over previous work with Co seeds owing to the higher magnetic susc... Read more

To quantitatively evaluate brain tissue and its corresponding function, knowledge of the 3D cellular distribution is essential. The gold standard to obtain this information is histology, a destructive and labor-intensive technique where the specimen is sliced and examined under a light microscope, providing 3D information at nonisotropic resolution. To overcome the limitations of conventional histology, we use phase-contrast X-ray tomography with optimized optics, reconstruction, and image an... Read more

The near-threshold behavior of long cracks is evaluated using pre-cracked flat dogbone specimens of a commercial aluminum alloy in two heat treatment states. Once the threshold was known, the crack initially introduced by cyclic compression was propagated under load control with approximately
constant range of the stress intensity factor at values close to the threshold values. The 3D morphology of the crack and the spatial distribution of the primary precipitates obtained by µ-CT were... Read more

The effect of the defect size and morphology on the fatigue damage evolution was analysed in a recycled Al-Si-Cu alloy by micro-computed tomography and scanning electron microscopy. Fatigue tests were performed and the different crack initiation scenarios were characterized and classified. The interaction between shrinkage and gas pores was the key crack initiation mechanism and the ß-Al5FeSi particles did not play any role in the crack initiation phase. However, crack path analysis indicate... Read more

Alveolar bone, together with the underlying trabecular bone, fulfils an important role in providing structural support against masticatory forces. Diseases such as osteoporosis or periodontitis cause alveolar bone resorption which weakens this structural support and is a major cause of tooth loss. However, the functional relationship between alveolar bone remodelling within the molar region and masticatory forces is not well understood. This study investigated this relationship by comparing m... Read more

Rapeseed is one of the most important and widely cultured oilseed crops for food and nonfood purposes worldwide. Neutral lipids are stored in lipid droplets (LDs) as fuel for germination and subsequent seedling growth. Most of the LD detection in seeds was still in 2D levels, and some of the details might have been lost in previous studies. In the present work, the configuration of LDs in seeds was obtained by confocal imaging combined with 3D reconstruction technology in Brassica napus<... Read more